1. Tolliver BA. Am J Gastroenterol 1994; 98:176 2. Sanders DS et al. Lancet 2001; 358: 1504 3. Owens Dm et a. Ann Intern Med 1995; 122:107 4. Adenij OA et al. Am J Gastroenterol 2002; 97:S273 5. Guthrie E et al. Br J Psychiaty 1993; 162:315 6. Brandt LJ et al. Am J Gastroenterol 2002; 97:S7 7. Jailwala J et al. Ann Intern Med 2000; 133:136. 8. Schoenfeld P et al. Gastroenterology 2002; 112: A1486 9. Nyhlin H, et al.Scand J Gastroenterol 2004;39:119 10.Locke III Gr et al. Mayo Clin Proc 2004;79:476 11.Tabas G. et al. Am J Gastroenterol May 2004;99:914-20 12.Cayley WE. Irritable bowel syndrome. BMJ 2005 Mar 18; 330:632 13. Ford AC et al. Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis. BMJ 2008;337 Dec 13:a2313 14. Ford AC et al. Efficacy of antidepressants and psychological therapies in irritable bowel syndrome: systematic review and meta-analysis. Gut. 2009 Mar; 58:367-78.